11/27/2023 0 Comments Expression after effects![]() Finally, staying up influenced myeloid subsets distribution and induced inflammation development and cellular senescence. Additionally, staying up reduced the differentiation and immune activity of cytotoxic cells, indicative of a predisposition to infection and tumor development. Participants subjected to staying up had increased T and plasma cell frequency, along with upregulated autoimmune-related markers and pathways in CD4 + T and B cells. Here we employed mass cytometry and single-cell RNA sequencing to obtain a comprehensive human immune cells landscape in the context of poor sleep, which was analyzed in the context of subset composition, gene signatures, enriched pathways, transcriptional regulatory networks, and intercellular interactions. ![]() ![]() With loss of sleep durations, poor sleep has been linked to the increased risks for diseases. Poor sleep has become an important public health issue.
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